Another summer is in full swing. The past year has left a lot of vivid impressions, and alas, not the most pleasant. Once again you have noticed a waistline that is getting bigger with extra pounds. What to do? The solution is immediately available – you need to start running. We all know that running is a universal tool for losing weight and maintaining good physical fitness. The scheme immediately appears in your head: start running, improve your discipline, lose extra pounds, show off to your colleagues and attract the attention of the opposite sex. A universal tool for solving your problems. Yes, it is, but here’s the problem, you have never read the instructions for such a tool. We present to you a complete guide to running for beginners. Get your shoelaces ready, because we are running a theoretical marathon. Disclaimer: Recommendations regarding joints, knees, heart, etc. should be discussed with your personal physician, as each reader has a different predisposition to injury,
Genetic Factors: Aging is intricately linked to genetic predispositions, as certain gene variants can influence the rate of aging and susceptibility to age-related conditions. Polymorphisms in genes associated with DNA repair, oxidative stress response, and longevity pathways can play a role in how individuals age. Cellular Damage: Progressive aging is associated with cumulative cellular damage, driven by various stressors, including environmental toxins, radiation, and endogenous metabolic processes. This damage encompasses genomic instability, epigenetic alterations, and protein dysfunction, all contributing to cellular senescence. Telomere Shortening: Telomeres, repetitive DNA sequences that protect chromosome ends, exhibit shortening with each cell division. Critically shortened telomeres impair cell replication, leading to cellular senescence, a hallmark of aging . Oxidative Stress: Oxidative stress arises from an imbalance between reactive oxygen species (ROS) production and